Get Straight to the Source of Hypophosphatasia

Hypophosphatasia (HPP) is a rare genetic (inherited) condition that affects how your bones and teeth develop. Specifically, it makes them soft and weak by affecting how they mineralize (calcify). HPP is a type of metabolic bone disease.

HPP ranges widely in severity. At its most mild, it significantly increases your risk of stress fractures in middle age. At its most severe, it can result in stillbirth or death shortly after birth.

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